Pulmonary function in ankylosing spondylitis

Exploring the relationship between spinal mobility and pulmonary function in AS

Pulmonary dysfunction in AS patients is common, but is is unclear if reduced spinal mobility and associated chest wall immobility OR direct inflammation of the lung parenchyma are responsible for increased fatigue and reduced capacity.

This study explores the relationship between spinal mobility (measured by the Bath Ankylosing Spondylitis Scales), radiographic changes in the spine (mSASSS), pulmonary function (FEV1 and FVC), pain, fatigue, and QOL in patient with AS.

Spinal mobility assessment indeed has a predictive value for respiratory capacity, with clinical implications (maintaining spinal mobility to prevent structural changes).

However, QoL and fatigue were only related to perceived physical condition and pain, suggesting that we need to focus more on pain management and moderate physical exercise as factors influencing work capacity.


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